Biomarker assays for all your drug development needs

Agilex Biolabs is a recognized leader in bioanalytical excellence. Our clients partner with us to navigate the complexities of bringing new drugs to market. We identify the best assay methodology to meet the clinical and regulatory needs for each project, for each client. When you partner with us, we can support your drug development with either our existing biomarker menu or more than 300 assays or develop and validate a suitable assay for your particular requirements. With 25 years of experience, your project will be delivered by the experts and with the highest quality results.

Validated fit for purpose assays

Compound ClassCompound (-metabolite)Species & MatrixLLOQ LevelLLOQ unitsTechnique
Angiotensin peptidesAngiotensin Ihuman plasma10pg/mlLC/MS/MS
 Angiotensin II 5pg/ml 
Androgen steroidsTestosteronehuman serum0.1ng/mlLC/MS/MS
 Dihydrotestosterone 0.1ng/ml 
CorticosteroidsTotal Cortisolhuman urine2ngmlLC/MS/MS
(enzyme hydrolysis)Total Cortisone 2ngml 
 Total Tetrahydrocortisone 40ngml 
 Total 5alpha Tetrahydrocortisol 40ngml 
 Total 5beta Tetrahydrocortisol 40ngml 
ProteinsVEGFhuman serum31.3pg/mlELISA
 Complement AP50human plasman/a Colorimetric
 KIM-1 /TIM-1 /HAVCRhuman urine0.156ng/mLELISA
 FGF-2human serum10pg/mlELISA
 IL-8human plasma0.5pg/mlMSD U-plex
 FGF-19human plasma15.6pg/mlELISA
 IL-6Rahuman serum15.6pg/mlELISA

Exploratory assays

Compound
Class
Compound (-metabolite)Species & MatrixLLOQ
Level
LLOQ
units
Technique
Sugar3-0-methylglucosehuman plasma2ug/ml
xProteinsMMP-3human serum0.156ng/mlELISA
CTX-IIhuman serum, plasma,
urine
0.156ng/mlELISA
ADAMTS5human serum0.156ng/mlELISA
alphaCTXhuman urine93.8pg/mlELISA
TIMP-1human serum0.156ng/mlELISA
Androgen
steroids
Testosteronehuman serum0.05ng/mLLC/MS/MS
A4 – Androstenedione0.05ng/mL
DHEA – Dehydroepiandrosterone2.5ng/mL
Estrogen
steroids
E1 – Estronehuman serum1ng/mLLC/MS/MS
E2 – Estradiol1ng/mL
E3 – Estriol1ng/mL
E4 – Estetrol1ng/mL
Metabolism
peptide
Motilinhuman serum20pg/mlLC/MS/MS
CatecholaminesNorepinephrinehuman plasma0.1ng/mlLC/MS/MS
Dihydroxyphenylethylene glycol
(DHPG)
0.1ng/ml